HCE is a Reference Center for Second Opinion, Electronic Medical Record, and a Global Platform for Cross Border Cooperation. HCE is defined as interconnected collaborative centers of professional knowledge and skills, which have common applicability to the benefit of all nations around the world. We speak here specifically of medical diagnostic, remote health care and treatment skills and training through knowledge sharing, second opinion, electronic medical records, which will facilitate effective healthcare knowledge deployment without undue concern for distance/local institutional resource.